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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NR2C1
All Species:
10
Human Site:
Y208
Identified Species:
18.33
UniProt:
P13056
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P13056
NP_001027458.1
603
67315
Y208
A
A
S
T
E
K
I
Y
I
R
K
D
L
R
S
Chimpanzee
Pan troglodytes
XP_001137621
678
75113
Y283
A
A
S
T
E
K
I
Y
I
R
K
D
L
R
S
Rhesus Macaque
Macaca mulatta
XP_001107297
554
61731
R165
I
N
K
H
H
R
N
R
C
Q
Y
C
R
L
Q
Dog
Lupus familis
XP_854792
605
67422
Y209
A
A
S
T
E
K
I
Y
I
R
K
D
L
R
S
Cat
Felis silvestris
Mouse
Mus musculus
Q505F1
590
65487
D200
E
K
I
Y
I
R
K
D
L
R
S
P
L
A
A
Rat
Rattus norvegicus
Q8VIJ4
590
65509
D200
E
K
I
Y
I
R
K
D
L
R
S
P
L
A
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510105
561
61971
P172
I
R
K
D
L
R
S
P
L
A
A
T
P
T
F
Chicken
Gallus gallus
O42101
501
57084
K112
K
C
L
S
V
G
M
K
L
E
A
V
R
A
D
Frog
Xenopus laevis
Q66J63
637
70793
S242
K
S
S
N
C
A
A
S
T
E
K
I
Y
I
R
Zebra Danio
Brachydanio rerio
Q06725
411
45463
G22
V
A
G
G
P
P
S
G
P
N
P
A
A
Q
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P16375
543
57969
H154
M
L
P
L
I
K
G
H
G
Q
D
M
L
T
S
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q9N4B8
615
68010
R201
C
P
V
T
K
F
H
R
N
R
C
Q
Y
C
R
Sea Urchin
Strong. purpuratus
Q26622
583
63834
A193
D
I
R
S
P
L
T
A
T
P
T
F
V
T
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
86.2
90.3
96
N.A.
87.5
87.5
N.A.
77.7
21.5
72.6
27
N.A.
22
N.A.
22.9
49
Protein Similarity:
100
87.6
91.2
97.6
N.A.
92.2
91.7
N.A.
84.7
40.9
82.7
42.7
N.A.
37.8
N.A.
42.1
65.1
P-Site Identity:
100
100
0
100
N.A.
13.3
13.3
N.A.
0
0
13.3
6.6
N.A.
20
N.A.
13.3
0
P-Site Similarity:
100
100
13.3
100
N.A.
33.3
33.3
N.A.
13.3
20
20
13.3
N.A.
33.3
N.A.
20
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
24
31
0
0
0
8
8
8
0
8
16
8
8
24
16
% A
% Cys:
8
8
0
0
8
0
0
0
8
0
8
8
0
8
0
% C
% Asp:
8
0
0
8
0
0
0
16
0
0
8
24
0
0
8
% D
% Glu:
16
0
0
0
24
0
0
0
0
16
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
8
0
0
0
0
0
8
0
0
8
% F
% Gly:
0
0
8
8
0
8
8
8
8
0
0
0
0
0
8
% G
% His:
0
0
0
8
8
0
8
8
0
0
0
0
0
0
0
% H
% Ile:
16
8
16
0
24
0
24
0
24
0
0
8
0
8
0
% I
% Lys:
16
16
16
0
8
31
16
8
0
0
31
0
0
0
0
% K
% Leu:
0
8
8
8
8
8
0
0
31
0
0
0
47
8
0
% L
% Met:
8
0
0
0
0
0
8
0
0
0
0
8
0
0
0
% M
% Asn:
0
8
0
8
0
0
8
0
8
8
0
0
0
0
0
% N
% Pro:
0
8
8
0
16
8
0
8
8
8
8
16
8
0
8
% P
% Gln:
0
0
0
0
0
0
0
0
0
16
0
8
0
8
8
% Q
% Arg:
0
8
8
0
0
31
0
16
0
47
0
0
16
24
16
% R
% Ser:
0
8
31
16
0
0
16
8
0
0
16
0
0
0
31
% S
% Thr:
0
0
0
31
0
0
8
0
16
0
8
8
0
24
0
% T
% Val:
8
0
8
0
8
0
0
0
0
0
0
8
8
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
16
0
0
0
24
0
0
8
0
16
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _